| Current
Chemical Biology
ISSN: 1872-3136 - Volume 2, 3 Issues, 2008

Editor-in-Chief:
Atta-ur-Rahman, FRS
HEJ Research Institute of Chemistry
University of Karachi
Karachi - 75270
Pakistan
Editorial
Advisory Board:
H.Y. Aboul-Enein (National
Research Centre, Cairo, Egypt)
B.B. Aggarwal (University of Texas, Houston, TX,
USA)
A. Alimonti (National Health Institute, Rome,
Italy)
M. Anzini (Universita’ di Siena, Siena,
Italy)
J. Aqvist (Uppsala University, Uppsala, Sweden)
A. Armstrong (Imperial College London, London,
UK)
Y. Asakawa (Tokushima Bunri University, Tokushima,
Japan)
D. Astruc (Université Bordeaux I,
Talence, France)
D.S. Auld (Harvard Medical School, Boston,
MA, USA)
J. Ausio (University of Victoria, Victoria,
Canada)
S.P. Bajaj (University of California Los
Angeles, Los Angeles, CA, USA)
P. Balaram (Indian Institute of Science,
Bangalore, India)
A. Ballabio (Telethon Institute of Genetics
and Medicine, Napoli, Italy)
G. Balme (Université Claude Bernard,
Villeurbanne, France)
R.A. Batey (University of Toronto, Toronto,
Canada)
D.J. Benos (University of Alabama at Birmingham,
Birmingham, AL, USA)
B. Berkhout (University of Amsterdam, Amsterdam,
The Netherlands)
I. Bertini (University of Florence, Sesto
Fiorentino, Italy)
A. Bianco (Università La Sapienza,
Rome, Italy)
R. Bilewicz (Warsaw University, Warsaw, Poland)
R.E. Blankenship (Washington University,
St. Louis, MO, USA)
M.L. Bolognesi (University of Bologna, Bologna,
Italy)
C. Bolm (RWTH Aachen University, Aachen,
Germany)
M.A. Bothwell (University of Washington,
Seattle, WA, USA)
S. Braese (Universität Karlsruhe, Karlsruhe,
Germany)
S. Brakmann (University of Dortmund, Dortmund,
Germany)
L. Brasili (University of Modena & Reggio
Emilia, Nodena, Italy)
M. Braun (Heinrich-Heine-Universität
Düsseldorf, Düsseldorf, Germany)
G. Brudvig (Yale University, New Haven, CT,
USA)
X.-H. Bu (Nankai University, Tianjin, China)
H. Budzikiewicz (Universität zu Köln,
Köln, Germany)
R. Bursi (NV Organon, Oss, The Netherlands)
S. Caddick (University College London, London,
UK)
G. Calo' (University of Ferrara, Ferrara,
Italy)
M. Canton (University of Padova, Padova,
Italy)
M.-F. Carlier (CNRS, Gif-sur-Yvette, France)
G. Caron (University of Torino (I), Torino,
Italy)
V.B. Carruthers (Johns Hopkins University,
Baltimore, MD, USA)
A. Catania (Fondazione IRCCS Ospedale Maggiore
Policlinico, Milano, Italy)
R. Chamberlin (University of California,
Irvine, CA, USA)
Y.-T. Chang (New York University, New York,
NY, USA)
D.Y. Chi (Inha University, Inchon, Korea)
J. Cinatl (Klinikum der Johann Wolfgang Goethe-Universität,
Frankfurt, Germany)
G.M. Clore (NIH, Bethesda, MD, USA)
J.M. Concellón (Universidad de Oviedo,
Oviedo, Spain)
G. Costantino (Universitd di Perugia, Perugia,
Italy)
B. Coulombe (Institut de recherches cliniques
de Montreal, Montreal, Canada)
P.G. Cozzi (University of Bologna, Bologna,
Italy)
C. Cremo (The University of Nevada, Reno,
NV, USA)
M.D. Cummings (Johnson & Johnson Pharmaceutical
Research and Development, L.L.C., Exton, PA, USA)
J. Cuppoletti (University of Cincinnati College
of Medicine, Cincinnati, OH, USA)
D.M. Cyr (University of North Carolina, Chapel
Hill, NC, USA)
S. Dai (Oak Ridge National Laboratory, Oak
Ridge, TN, USA)
T.M. Dawson (Johns Hopkins University School
of Medicine, Baltimore, MD, USA)
U.R. Desai (Virginia Commonwealth University,
Richmond, VA, USA)
G.R. Desiraju (University of Hyderabad, Hyderabad,
India)
G. Dormán (Albany Molecular Research
Institute, Budapest, Hungary)
S. Ducki (University of Salford, Salford,
UK)
P.J. Dyson (Ecole Polytechnique Fédérale
de Lausanne, Lausanne, Switzerland)
F. Edelmann (Otto-von-Guericke-Univerity
at Magdeburg, Magdeburg, Germany)
T. Elliott (University of Southampton School
of Medicine, Southampton, UK)
R.R. Ernst (Swiss Federal Institute of Technology
Zurich, Zurich, Switzerland)
I.J.S. Fairlamb (University of York, York,
UK)
V.E. Fedorov (Siberian Branch of Russian
Acad. of Sci., Novosibirsk, Russia)
L. Feng (Tsinghua University, Beijing, China)
A.P. Fields (Mayo Clinic Comprehensive Cancer
Center, Jacksonville, FL, USA)
S. Freeman (University of Manchester, Manchester,
UK)
A. Ganesan (University of Southampton, Southampton,
UK)
J. Gao (University of Minnesota, Minneapolis,
MN, USA)
A. Gasco (University of Turin, Turin, Italy)
V.A. Gault (University of Ulster, Coleraine,
Northern Ireland)
E. Gazit (Tel Aviv University, Tel Aviv,
Israel)
B. Giese (University of Basel, Basel, Switzerland)
E. Giralt (Institut de Recerca Biomèdica
de Barcelona, Barcelona, Spain)
R.A. Glennon (Virginia Commonwealth University,
Richmond, VA, USA)
H. Goldfine (University of Pennsylvania,
Philadelphia, PA, USA)
A. Gomtsyan (Abbott Laboratories, Abbott
Park, IL, USA)
B. Gong (State University of New York, Buffalo,
NY, USA)
C. Gowda (Pennsylvania State University College
of Medicine, Hershey, PA, USA)
A.M. Gronenborn (Univ. of Pittsburgh Sch.
of Med., Pittsburgh, PA, USA)
H. Grubmueller (Max-Planck-Inst. for Biophys.
Chem., Goettingen, Germany)
R.I. Gumport (University of Illinois, Urbana,
IL, USA)
M.J. de Groot (Pfizer Global Res. and Develop.,
Sandwich Laboratories, Kent, UK)
R. Gust (Free University Berlin, Berlin,
Germany)
D. Hall (University of Alberta, Alberta,
Canada)
B. Han (Chinese Academy of Sciences, Beijing,
China)
J. Han (The Scripps Research Institute, La
Jolla, CA, USA)
Y. Hashimoto (The University of Tokyo, Tokyo,
Japan)
C. Haskell-Luevano (University of Florida,
Gainesville, FL, USA)
B. Hauer (BASF Aktiengesellschaft, Ludwigshafen,
Germany)
M. Hengartner (University of Zurich, Zurich,
Switzerland)
S.A. Henry (Cornell University, Ithaca, NY,
USA)
W. Hinrichs (University of Greifswald, Greifswald,
Germany)
M. Hippler (University of Muenster, Muenster,
Germany)
M. Hirama (Tohoku University, Sendai, Japan)
J. Hiscott (Jewish General Hospital, Montreal,
Canada)
W.J. Hoekstra (GlaxoSmithKline Inc., Research
Triangle Park, NC, USA)
F. Hof (University of Victoria, Victoria,
Canada)
H.-J. Hofmann (Universität Leipzig,
Leipzig, Germany)
S. Homans (University of Leeds, Leeds, UK)
H. Höpfl (Universidad Autónoma
del Estado de Morelos, Cuernavaca, Mexico)
R. Horuk (Berlex Biosciences, Richmond, CA,
USA)
N.V. Hud (Georgia Institute of Technology,
Atlanta, GA, USA)
A. Imberty (CERMAV-CNRS, Grenoble Cedex,
France)
R.J. Isfort (Procter & Gamble Pharmaceuticals,
Mason, OH, USA)
K.A. Jacobson (NIH, Bethesda, MD, USA)
K.-T. Jeang (NIH, Bethesda, MD, USA)
A.K.-Y. Jen (University of Washington, Seattle,
WA, USA)
F. Jian (Qingdao University of Science and
Technology, Qingdao, China)
L. Jiang (Chinese Academy of Sciences, Beijing,
China)
D.L.N. Johnson (University of Oxford, Oxford,
UK)
A.L. Jonsson (Umea University, Umea, Sweden)
P. Joseph-Nathan (Instituto Politécnico
Nacional, Mexico City, Mexico)
Y. Kayaki (Tokyo Institute of Technology,
Tokyo, Japan)
P.A. Keller (University of Wollongong, Wollongong,
Australia)
Z. Kelman (University of Maryland Biotechnology
Institute, Rockville, MD, USA)
B.K. Keppler (University of Vienna, Vienna,
Austria)
H. Kessler (Inst. fuer Org. Chem. und Biochem.,
Garching, Germany)
Y. Kiso (Kyoto Pharmaceutical University,
Kyoto, Japan)
Y. Kita (Osaka University, Osaka, Japan)
D. Klenerman (Cambridge University, Cambridge,
UK)
B. Koenig (University of Regensburg, Regensburg,
Germany)
U. Koert (Philipps-Universität Marburg,
Marburg, Germany)
K. Koide (University of Pittsburgh, Pittsburgh,
PA, USA)
H. Kotsuki (Kochi Universiy, Kochi, Japan)
A.P. Kozikowski (University of Illinois at
Chicago, Chicago, IL, USA)
R. Krumlauf (Stowers Inst. for Med. Res.,
Kansas City, MO, USA)
W. Kunz (University of Regensburg, Regensburg,
Germany)
M.K. Lakshman (The City University of New
York, New York, NY, USA)
J. Lange (Solvay Pharmaceuticals B.V., Weesp,
The Netherlands)
S. LaPlante (Boehringer Ingelheim (Canada)
Ltd., Montreal, Quebec, Canada)
S.A. Laufer (Eberhard-Karls-University Tuebingen,
Tuebingen, Germany)
P.A. Lay (The University of Sydney, Sydney,
Australia)
H.C. Lee (University of Minnesota, Minneapolis,
MN, USA)
P. le Floch (Ecole Polytechnique, Palaiseau
Cedex, France)
A. Levitzki (The Hebrew University of Jerusalem,
Jerusalem, Israel)
S.V. Ley (University of Cambridge, Cambridge,
UK)
J. Li (Pacific Northwest National Laboratory,
Richland, WA, USA)
Y. Li (Tsinghua University, Beijing, China)
K.-J. Lin (National Chung Hsing University,
Taichung, Taiwan)
Y. Lin (Pacific Northwest National Laboratory,
Richland, WA, USA)
B.H. Lipshutz (University of California,
Santa Barbara, CA, USA)
C.-M. Liu (Institute of Chemistry, Chinese
Academy of Sciences, Beijing, China)
A. Llebaria (Research Unit on BioActive Molecules,
Barcelona, Spain)
R. Lomoth (Uppsala University, Uppsala, Sweden)
Y. Lu (Tulane University, New Orleans, LA,
USA)
B. Ma (Bristol-Myers Squibb, Wallingford,
CT, USA)
D. Ma (Chinese Academy of Sciences, Shanghai,
China)
H.-M. Ma (Institute of Chemistry, Chinese
Academy of Sciences, Beijing, China)
J. Ma (UMDNJ-Robert Wood Johnson Medical
School, Piscataway, NJ, USA)
S. Ma (Zhejiang University, Hangzhou, China)
L.R. MacGillivray (University of Iowa, Iowa
City, IA, USA)
T. Maina (National Center for Scientific
Research “Demokritos”, Athens, Greece)
A. Makriyannis (Bouve Coll. Hlth. Sci. Northeastern
Univ., Boston, MA, USA)
J.J. Manfredi (Mount Sinai School of Medicine,
New York, NY, USA)
A. Marabotti (Italian National Research Council,
Avellino, Italy)
T. Martinek (University of Szeged, Szeged
Eotvos, Hungary)
B. Mayer (Karl-Franzens-University Graz,
Graz, Austria)
J.P. Mayer (Lilly Corporate Center, Indianapolis,
IN, USA)
A. de Meijere (Georg-August-Universitaet
Goettingen, Goettingen, Deutschland)
P. Metz (Technische Universität Dresden,
Dresden, Germany)
W.A. Metz (Sanofi Aventis Pharmaceuticals,
Bridgewater, NJ, USA)
Y. Mo (Western Michigan University, Kalamazoo,
MI, USA)
N.J. de Mol (Utrecht University, Utrecht,
The Netherlands)
K. Morikawa (Osaka University, Osaka, Japan)
L. Morin-Allory (University of Orléans,
Orléans Cedex, France)
S. Moro (University of Padova, Padova, Italy)
J.D. Morrow (Vanderbilt University, Nashville,
TN, USA)
A. Müller (Universität Bielefeld,
Bielefeld, Germany)
O. Müller (Max-Planck Institute of Molecular
Physiology, Dortmund, Germany)
P.V. Murphy (University College Dublin, Dublin,
Ireland)
G.H. Nancollas (The State University of New
York, Amherst, NY, USA)
W. Nam (Ewha Womans University, Seoul, Korea)
K. Nagasawa (Tokyo University of Agriculture
and Technology, Tokyo, Japan)
N. Neamati (Universiy of Southern California,
Los Angeles, CA, USA)
S.J. Ono (Emory University , London, UK)
T. Owa (Eisai Co., Ltd., Ibaraki, Japan)
S.-E. Park (Inha University, Incheon, Korea)
K.S. Patrick (Medical University of South
Carolina, Charleston, SC, USA)
S. Pennington (University College Dublin,
Dublin, Ireland)
V. Pittalà (Università degli
Studi di Catania, Catania, Italy)
M.R. Player (Johnson & Johnson Pharm.
Res. & Develop., L.L.C, Exton, PA, USA)
P. Potter (St. Jude Children’s Research
Hospital, Memphis, TN, USA)
M. Quan (Bristol-Myers Squibb Company, Pennington,
NJ, USA)
P. Quinn (King's College, London, UK)
T. Rabilloud (INSERM, Grenoble Cedex, France)
S.W. Ragsdale (University of Nebraska, Lincoln,
NE, USA)
C.G. Riordan (University of Delaware, Newark,
DE, USA)
M.A. Rizzacasa (The University of Melbourne,
Victoria, Australia)
D.D. Roberts (NIH, Bethesda, MD, USA)
P.J. Robinson (Children’s Medical Research
Institute, Sydney, Australia)
A. Rogach (Ludwig-Maximilians-Universitaet
Muenchen, Munich, Germany)
E.B. Romero (Universidad Autonoma de Madrid,
Madrid, Spain)
D.W. Rose (Veteran’s Medical Research
Foundation, La Jolla, CA, USA)
A. Ross (UMASS Medical School, Worcester,
MA, USA)
S. Ruchirawat (Chulabhorn Research Institute,
Bangkok, Thailand)
T. Russo (University of Napoli Federico II,
Napoli, Italy)
M. Santoro (University "Federico II"
of Naples, Napoli, Italy)
M. Sarikaya (University of Washington, Seattle,
WA, USA)
K. Satake (Okayama University, Okayama, Japan)
A.P.H.J. Schenning (Eindhoven Univ. of Technol.,
Eindhoven, The Netherlands)
H. Scheraga (Cornell University, Ithaca,
NY, USA)
G. Schneider (Johann Wolfgang Goethe-University,
Frankfurt, Germany)
W. Schrader (Max-Planck-Institut für
Kohlenforschung, Mülheim, Germany)
H. Schwalbe (Johann Wolfgang Goethe-University
Frankfurt, Frankfurt, Germany)
P.H. Seeberger (Swiss Federal Inst. of Technol.
(ETH) Zürich, Zürich, Switzerland)
T. Shimizu (Tohoku University, Sendai, Japan)
I. Shin (Yonsei University, Seoul, Korea)
M. Shionoya (The University of Tokyo, Tokyo,
Japan)
J. Shlomai (The Hebrew University-Hadassah
Medical School, Jerusalem, Israel)
F. Sieber (Medical College of Wisconsin,
Milwaukee, WI, USA)
M. Sieber-Blum (Medical College of Wisconsin,
Milwaukee, WI, USA)
R. Silvestri (University “La Sapienza”,
Rome, Italy)
T.J. Simpson (University of Bristol, Bristol,
UK)
R. Simpson (Ludwig Institute for Cancer Research,
Parkville, Australia)
P. Sinay (Ecole Normale Superieure, Paris,
France)
K. Soai (Tokyo University of Science, Tokyo,
Japan)
D.V. Soldatov (Russian Academy of Sciences,
Novosibirsk, Russia)
M. Sollogoub (Institut de chimie moléculaire,
Paris Cedex, France)
A.J. Souers (Abbott Laboratories, Abbott
Park, IL, USA)
S. Spiro (University of Texas at Dallas,
Richardson, TX, USA)
D. Spitzner (University of Stuttgart, Stuttgart,
Germany)
S.S. Stojilkovic (NIH, Bethesda, MD, USA)
B.M. Stoltz (California Institute of Technology,
Pasadena, CA, USA)
J. Storey (University of Aberdeen, Aberdeen,
UK)
W.K. Surewicz (Case Western Reserve University,
Cleveland, OH, USA)
C. Szantay (Technical University of Budapest,
Budapest, Hungary)
W. Tam (University of Guelph, Guelph, Canada)
F. Tanaka (The Scripps Research Institute,
La Jolla, CA, USA)
N. Taniguchi (Osaka University Graduate School
of Medicine, Osaka, Japan)
N. Tao (Arizona State University, Tempe,
AZ, USA)
R.E. Taylor (University of Notre Dame, Notre
Dame, IN, USA)
D.B. Teplow (David Geffen School of Medicine
at UCLA, Los Angeles, CA, USA)
E.A. Theodorakis (University of California,
San Diego, CA, USA)
J.A. Thomas (University of Sheffield, Sheffield,
UK)
F. Tillequin (University of Paris, Paris,
France)
P.J. Tonge (Stony Brook University, Stony
Brook, NY, USA)
M. Tori (Tokushima Bunri University, Tokushima,
Japan)
B.M. Trost (Stanford University, Stanford,
CA, USA)
V.V. Tsukruk (Georgia Institute of Technology,
Atlanta, GA, USA)
N.P.E. Vermeulen (Vrije Universiteit, Amsterdam,
The Netherlands)
R. Verpoorte (Leiden University, Leiden,
The Netherlands)
G. Vistoli (University of Milan, Milan, Italy)
N. Vitale (Université Louis Pasteur,
Strasbourg Cedex, France)
J.J. Vittal (National University of Singapore,
Singapore, Singapore)
W. Voelter (Eberhard-Karls-University of
Tuebingen, Tuebingen, Germany)
R.C. Wade (EML Research gGmbH, Heidelberg,
Germany)
H. Waldmann (Max Planck Institute of Molecular
Physiology, Dortmund, Germany)
L.-J. Wan (Chinese Academy of Sciences, Beijing,
China)
C.-C. Wang (Chinese Academy of Sciences,
Beijing, China)
J. Wang (Encysive Pharmaceuticals Inc., Houston,
TX, USA)
M.-X. Wang (Chinese Academy of Sciences,
Beijing, China)
P.G. Wang (The Ohio State University, Columbus,
OH, USA)
X.-F. Wang (Duke University Medical Center,
Durham, NC, USA)
S.M. Weinreb (Pennsylvania State University,
Philadelphia, PA, USA)
H. Weinstein (Weill Medical College of Cornell
University, New York, NY, USA)
T. Wieder (University of Tuebingen, Tuebingen,
Germany)
R.M. Williams (Colorado State University,
Fort Collins, CO, USA)
C.C. Wilson (University of Glasgow, Glasgow,
USA)
W. Wintermeyer (University of Witten-Herdecke,
Witten, Germany)
T. Wirth (Cardiff University, Cardiff, UK)
V. Wittmann (Universitaet Konstanz, Konstanz,
Germany)
W.-D. Woggon (University of Basel, Basel,
Switzerland)
W.-T. Wong (The University of Hong Kong,
Pokfulam Road, Hong Kong)
Z.-J. Yao (Chinese Academy of Sciences, Shanghai,
China)
K. Yamamoto (Kyushu University, Fukuoka,
Japan)
D.S.-C. Yang (McMaster University, Hamilton,
Canada)
T. Yokomatsu (Tokyo University of Pharmacy
and Life Science, Tokyo, Japan)
B. Yu (Chinese Academy of Sciences, Shanghai,
China)
J. Yu (Jilin University, Changchun, China)
M. Yus (Universidad de Alicante, Alicante,
Spain)
G. Zanoni (University of Pavia, Pavia, Italy)
J. Zemlicka (Wayne State University School
of Medicine, Detroit, MI, USA)
H.C. Zeng (National University of Singapore,
Kent Ridge Crescent, Singapore)
Y. Zhou (Indiana University, Indianapolis,
IN, USA)
T. Ziegler (University of Tuebingen, Tuebingen,
Germany)
Y. Zick (Weizmann Institute of Science, Rehovot,
Israel) |