Current Pharmaceutical Design

ISSN: 1381-6128 - Volume 14, 36 Issues, 2008

Online Abstract Submission

Instructions for Authors

MANUSCRIPTS SUBMISSION: Authors wishing to submit comprehensive reviews in any frontier area of drug design should contact the Executive Guest Editor of the relevant field with the title and a one page summary of the proposed contents. A copy of the summary proposal should also be sent to the Journal Editor-in-Chief. Should authors wish to submit a review article in any other area of drug design not stated below, then please first submit a summary proposal to the Editor-in-Chief, Prof. William A. Banks, GRECC, Veterans Affairs Medical Center-St. Louis & Saint Louis University School of Medicine, Division of Geriatrics, Department of internal medicine, 915 North Grand Blvd., St. Louis, MO 63106, USA Fax: +1 314-289-6734; e-mail :bankswa@slu.edu Each first named author who publishes an article will receive a free one year subscription to the journal (of the current volume). The Executive Editors for the various fields are as follows: Cardiovascular and Hematological Agents. Ho-Sam Ahn, (USA), e-mail: ho-sam.ahn@spcorp.com Cardiovascular and Hematological Agents. Johann Wolfgang Auer, (Austria), e-mail: johann.auer@khwels.at COX 2 Inhibitors. Angel Lanas Arbeloa (Spain), analas@doymanet.es CNS Agents: Masato Asanuma, (Japan), e-mail: asachan@cc.okayama-u-ac.jp Anti-Infective Agents: Mitchell A. Avery/Vassil St. Georgiev, (USA), e-mail: vg8q@nih.gov The Blood Brain Barrier in Health & Disease: William A. Banks, (USA), e-mail: bankswa@slu.edu Genomics and the Prospects of Antibacterial & Antifungal Agents: John F. Barrett, (USA), e-mail: john.barrett@bms.com Anti-Infective Agents: Fatima Z. Basha/Les Mitscher, (USA), e-mail: fatima.z.basha@abbott.com Anti-Cancer Drugs: E.S. Bergmann-Leitner, (USA), e-mail: esbl@helix.nih.gov Peptide Radiopharmaceuticals: Jay Elliot Blum, (USA), e-mail: peptidedoc@cox.net Anti-Angiogenesis Agents: Maurizio Botta, (Italy), e-mail: manettif@unisi.it Development of Cytokines for Use in Treatment of Blood Disorders: Ken Bradstock, (Australia), e-mail: Bradstok@icpmr.wsahs.nsw.gov.au COX-II Inhibitors: Peter Brooks, (Australia), e-mail: lineman@mailbox.uq.edu.au Kinase and Phosphatase Drug Discovery and Design. Dirksen Bussiere, (USA), e-mail: Dirksen_Bussiere@chiron.com Anti-Cancer Agents: Giovanni Capranico, (Italy), e-mail: giovanni.capranico@unibo.it Anti-Inflammatory and Antiallergy Agent: Tz-Chong Chou, (Taiwan), e-mail: tcchou@ms5.hinet.net Enzyme / Protease Inhibitors: Nestor Omar Concha, (USA), e-mail: Nestor_O_Concha@gsk.com Radiolabelled Compounds for Drug Discovery and Development: G.J.R. Cook, (UK), e-mail: gary.j.cook@kcl.ac.uk Anti-Thrombotics. Dermot Cox, (Ireland), e-mail: dcox@rcsi.ie Cell Biology and Chemotherapy of Trypanosomiasis and Leishmaniasis: Wanderley de Souza, (Brazil), e-mail: wsouza@sect.rj.gov.br Death Receptor Ligands: E.G. Elisabeth de Vries, (The Netherlands), e-mail: e.g.e.de.vries@int.azg.nl Antimetabolite Agents: Galal Hamza Elgemeie, (Egypt): e-mail: rughe@rusys.eg.net Neuropeptide-based Drug Design: Illana Gozes, (Israel), e-mail: igozes@post.tau.ac.il Analgesic Drug Design and Discovery: Gurmit Grewal, (USA), e-mail: Gurmit.Grewal@ucb-group.com Pharmacophore Elucidation & Their Use in Drug Design. Salvatore Guccione, (Italy), e-mail: guccione@mbox.unict.it Nitric Oxide in Drug Design & Discovery: D. Hadjipavolou-Litina, (Greece), e-mail: hadjipav@pharm.auth.gr Recent Therapeutic Approaches to the Treatment of cognitive Impairment and Dementia: Bernd Ibach (Germany), e-mail: andrea.pielmeier@klinik.uni-regensburg.de Cardiovascular and Hematological Agents. Makoto Katoh, (Japan), e-mail: katoh-m@tanabe.co.jp Anti-Inflammatory and Anti-Allergy Agents: Milton John Kiefel, (Australia), e-mail: m.kiefel@mailbox.gu.edu.au Radiopharmaceuticals in Drug Discovery and Development: Michael Kassiou (Australia), e-mail: mkassiou@med.usyd.edu.au Anti-Cancer Agents: Alan P. Kozikowski / Maurizio Pellecchia (USA / USA), e-mail: kozikowa@uic.edu / e-mail: mpellecchia@burnham.org Ion Channels as a Target for Drug Design: Kwok-Keung Tai (USA) kktai@yahoo.com Antihypertensive Drugs: Gregory Y.H. Lip, (UK) e-mail: G.Y.H.Lip@bham.ac.uk Cardiovascular and Hematological Agents. Eva Lonn, (Canada), e-mail: eva@ccc.mcmaster.ca Allergy-Asthma: Jan Lotvall, (Sweden), e-mail: jan.lotvall@hjl.qu.se Infectious Disease-Drug Delivery to Treat: Shigefumi Maesaki (Japan), e-mail: maesaki@saitama-med.ac.jp Angiogenesis Agents: Cezary Marcinkiewicz, (USA), e-mail: cmarcink@nimbus.ocis.temple.edu Protease Inhibitors: Robert W. Marquis, (USA), e-mail: Robert_W_Marquis@sbphrd.com Update in the Medical Treatment of Head Injured Patients in Relation to Outcome: Maria Mataro/J. Sahquillo (Spain), e-mail: mmataro@terra.es Antithrombotic Drug Design. Hiroyuki Matsuno, (Japan), e-mail: leuven@cc.gifu-u.ac.jp Applications of ACE Inhibitors and A2 Receptor Blockers: Agostino Molteni, (USA), e-mail: moltenia@umkc.edu Antihypertensive: Trefor Morgan, (Australia), e-mail: t.morgan@physiology.unimelb.edu.au Osteoporosis: Paul Morley, (Canada), e-mail: paul.morley@nrc.ca Purine Receptors as Targets for Future Drugs: Christa E. Mueller, (Germany), e-mail: christa.mueller@uni-bonn.de Anti-Cancer Agents: I. Niculescu-Duvaz, (UK), e-mail: ion@icr.ac.uk Protease Inhibitors: Vicki L. Nienaber, (USA), e-mail: vicki.nienaber@corvas.com Cytokines and Anti-cytokines: Atsushi Oda, (Japan), e-mail: aoda@med.hokudai.ac.jp DNA Topoisomerases as Targets for Anticancer Drugs: Neil Osheroff, (USA), e-mail: osheron@ctrvax.vanderbilt.edu HIV Drug Design (Anti-HIV Agents): Keykavous Parang, (USA), e-mail: kayparang@hotmail.com Tumour Selective Drug Activation: Laurence H. Patterson, (UK), e-mail: medchem@ulsop.ac.uk Bactericidal Peptides: Antonio Pellegrini, (Switzerland), e-mail: pellegrinia@access.unizh.ch Drugs in Interventional Cardiology: Peter W. Radke, (Germany), e-mail: PRadke@ukaachen.de Transplantation-Anti-Rejection Agents. Markus Richter, (Germany), e-mail: drrichter@gmx.net Obesity Drug Design (Anti-Obesity Agents): J.C. Russell, (Canada), e-mail: Jim.Russell@ualberta.ca Cancer Vaccine and Immunotherapy: Farid Saleh, (Kuwait), e-mail: fred@hsc.edu.kw Enzyme Inhibition: Michel Salzet, (France), e-mail: michel.salzet@univ-lille1.fr Cytokines: Computer Aided Design of Proteins for Therapeutic Use: Catherine H. Schein, (USA), e-mail: chschein@utmb.edu G Protein-Coupled Receptor Drug Targets. Patrick Sexton, (Australia), e-mail: p.sexton@hfi.unimelb.EDU.AU Glutamate Receptor: Sandor Solyom (Hungary), e-mail: h13759sol@helka.iif.hu Protein MIisfolding Disorders: Claudio Soto (Switzerland) e-mail: claudio.Soto@serono.com Autoimmune Diseases: D. Stahl, (Germany), e-mail: stahld@uni-muenster.de Peptides and Peptidomimetics as Anti-cancer Therapeutics as Anti-Cancer Therapeutics: Nadya Tarasova, (USA), e-mail: tarasova@ncifcrf.gov Recent Advances in Developmental Toxicology: Gian Mario Tiboni (Italy), e-mail: tiboni@phobos.unich.it Regulatory Peptides: Nese Tuncel (Turkey), e-mail: ntuncel@ogu.edu.tr PET and SPECT in Drug Design: Aren van Waarde, (The Netherlands), e-mail: aren@pet.azg.nl Endocrine & Metabolic Agents: Allan Wagman, (USA), e-mail: allan_wagman@chiron.com Antihypertensive Agents: Jiguang Wang, (Belgium), e-mail: Jiguang.Wang@med.kuleuven.ac.be Obesity Drug Design: Christian Weyer, (USA), e-mail: cweyer@amylin.com Central Nervous System Agents: Joseph Yevich/David W. Smith, (USA), e-mail: yevichj@bms.com, e-mail: smithdw@bms.com Recent Advances in Antiviral Agents Shin-Ru Shih (Taiwan), e-mail: srshih@mail.cgu.edu.tw Computational biology and drug design Xiaoqin Huang (USA), e-mail: xhuan5@email.uky.edu, Antidepressant Drug Design Lee E. Schechter, email: schechl@wyeth.com, HIV Entry Inhibitors Shibo Jiang, email: sjiang@nybloodcenter.org , Direct Thrombin Inhibitors and Synthetic F Xa Inhibition, Giuseppe G. Nenci, e-mail: medvasc@unipg.it Spinal Cord Injury and Repair Weihong Pan (USA), email: weihong.pan@pbrc.edu

Manuscript Preparation: The manuscript should be approximately up to 50 pages in length for full-length reviews and 30 pages for a mini-review, All pages should be numbered. Abbreviations should be defined the first time that they are used in the manuscript and a list of abbreviations used should be provided. Spelling may be in British or American but a mixture is not acceptable.

The manuscript, written in English, should be typed in double spacing throughout on A-4 or American quarto paper. Dot matrix print or any print that is difficult to read is unacceptable. Two copies of the manuscript must accompany the original (along with a computer disk) and should be sent to the Editor at his address. Abbreviations used should be provided. Please provide your telephone and fax numbers along with your e-mail address with all submissions to the Guest Editor.

Manuscript Organization: The manuscript should be divided as: Title page, abstract and the main text. The text may be subdivided further according to the areas to be discussed. This should be followed by the Acknowledgement (if any) and Reference sections. The first page should contain the title, the authors names (initials and surname only), with an asterisk in front of the name of the principal author.

Conflict of Interest: Financial contributions to the work being reported should be clearly acknowledged, as should any potential conflict of interest.

Abstract: The abstract should not exceed 250 words and it should condense the essential features of the review article, with the focus on the major advances in the field.

Key Words: Authors must supply up to eight key words along with their manuscript.

Text: The main text should begin on a separate page and it may be subdivided into separate sections. The review article should mention any previous important reviews in the field and contain a comprehensive discussion starting with the general background of the field. It should then go on to discuss the salient features of recent developments. The authors should avoid presenting material, which has already been published in a previous review. The reference numbers should be given in square brackets in the text. Acknowledgements should be kept to a minimum.

Tables:

  • Data Tables should be submitted in Microsoft Excel or in Microsoft Word table format.
  • Each table should include a title/caption explaining what the table shows. Detailed legends may then follow.
  • Tables should be given on separate pages with indications on the left hand margin to the text, as to the appropriate placement of the tables.
  • Tables should not contain vertical rules.
  • Columns and rows of data should be made visibly distinct by ensuring the borders of each cell display as black lines.
  • Tables should be numbered consecutively in order of their citation in the body of the text, with Arabic numerals.
  • If a reference is cited in both the table and text, insert a lettered footnote in the table to refer to the numbered reference in the text.
  • Tabular data provided as additional files can be submitted as an Excel spreadsheet.

Figures / Illustrations:

All authors must strictly follow the guidelines below for preparing illustrations for publication in Current Pharmaceutical Design.

Editorial Requirements:

The quality of the illustrations printed in the journal largely depends on the quality of the figures/illustration provided by the author. In preparing artwork or graphics for publication, keep in mind the following points.

  • Submit the original artwork or a photographic print of the original for publication.
  • Do not submit photocopies. (Hardcopy submission requirement)
  • Illustrations should be provided as separate files, not embedded in the text. (Hardcopy submission requirement)
  • Remove all color from graphics except for those illustrations (Greyscale), which are intended to be printed in color.
  • Good quality of hardcopy originals are a requirement.
  • Figures should be referred to as “Fig. (1)”, “Fig. (2)” etc. in the text with figure numbers in bold within round bracket.
  • Revised manuscripts should contain a complete set of artwork and photographs.

Technical Details:

  • Figures should be provided on high quality, white, smooth opaque paper. (Hardcopy requirement)

Format & Resolution:

  • The following file formats can be accepted. (Preference in order of appearance) : PDF, TIFF, JPEG, GIF
  • Illustrations must fit a single or double column format on the journal page, according to the following guideline below:


HEIGHT
WIDTH
SINGLE COLUMN
24 cm (max)
8.5 cm (max)
DOUBLE COLUMN
24 cm (max)
18 cm (max)

  • Whenever possible, submit graphics that do not have to be reduced to fit the standard figure size.
  • Use the best resolution available (hardcopy submission requirement). For online submission the maximum resolution is 300 dpi.
  • Avoid textures and shadings giving a three-dimensional effect to the illustration.
  • Symbols and lettering in the illustration should be of similar size.
  • Smaller lettering is used.
  • Font: Times New Roman or Helvetica is preferable. Font size: 10pt (maximum)
  • Line drawings should have clear and sharp lines and should be of uniform density. Moreover, lines should be continuous without any breaks.
  • Do not use lines thinner than 1 point.

Color Figures / Illustrations:

  • The cost for the first published page of color figures is US$ 730; the second additional page will be for US$ 535, and each subsequent page for US$ 360.
  • Color figures should be supplied in CMYK not RGB colors.
  • Required resolution for online submission is 300 dpi. In case of hardcopy submission, please use the maximum resolution available. In case the figure(s) are of an inferior quality they will need to be improved either by the author or by the publisher on a charged basis.

Photographs:

Submit high-contrast prints that are of single- or double-column width so that they will not have to be reduced when printed. Negatives are not acceptable. However, in case of hardcopy submission, color illustrations and plates can be published from 35 mm color slides.

Chemical Structures: Chemical structures must be prepared according to the guidelines below.

Structures should be prepared using a suitable drawing program e.g. ChemDraw and provided as separate file, submitted both on disk and in printed formats.
Numbers in bold should identify all chemical structure. If a name is also used to describe the compound, the associated number if required, should be in bold in parenthesis, e.g. "compound (1)".

Structure Drawing Preferences:

[As according to the ACS style sheet]

Drawing Settings:

Chain angle       120°
Bond spacing    18% of width
Fixed length       14.4 pt (0.500cm, 0.2in)
Bold width          2.0 pt (0.071cm, 0.0278in)
Line width           0.6 pt (0.021cm, 0.0084in)
Margin width       1.6 pt (0.096cm)
Harsh spacing    2.5 pt (0.088cm, 0.0347in)

Text settings:

Font                    Times New Roman / Helvetica
Size                     8pt

Under the Preference Choose:

Units                    points
Tolerances          3 pixels

Under Page Setup Use:

Paper                  US letter
Scale                  100%


Reference: References should be numbered sequentially in square brackets [ ] in the text and listed in the same numerical order in the reference section.
All references must be complete and accurate. Online citations should include date of access. Journal titles should conform to the present Index Medicus abbreviations. It is necessary to list all authors if the total number of authors is 6 or less and for more than six authors use et al. References should be listed in the following Vancouver style:

Typical Paper Reference:

Boehm M, Nabel EG. Angiotensin-converting enzyme 2--a new cardiac regulator. N Engl J Med 2002; 347: 1795-7.
SoRelle R. Long reach of the N-terminal of B-type natriuretic peptide. Circulation 2002; 106: 9059-63.

Typical Chapter Reference:

Stevenson WG, Friedman PL. In: Hennekens CH Ed, Clinical trials in cardiovascular disease. Philadelphia, WB Saunders Co. 1999; 217-30

Abstracts, unpublished data and personal communications (which can only be included if prior permission has been obtained) should not be given in the references section but they may be mentioned in the text and details provided as footnotes.

Manuscript Submission: Two copies of the manuscript must accompany the original along with the soft copy of the manuscript on a computer floppy disk(s) in MS Word file format (or created in any other well-known word processing software) should be submitted. To achieve rapid publication authors are encouraged to e-mail or fax their submission to the appropriate editorial office (see above) at the same time that they mail the manuscript. For even faster publication, authors are encouraged to submit their entire manuscript via BenthamÆs online submission service (see below). Authors must provide their full address, telephone and Fax numbers with E-Mail address with all submissions.

For expedient and speedy reviewing of author's manuscripts, authors are strongly advised to include the PDF file of their manuscript on a floppy or zip disk, into the mailing material. At the same time the package is mailed, please also send by e-mail a copy of the PDF file of the manuscript to the editorial office.

Online Manuscript Submission: (preferable)
To facilitate speedy and cost-effective submission of abstracts and manuscripts, an online submission and tracking service via Internet is being offered. Once the Editor-in-Chief of the journal has accepted your abstract, we would prefer that you submit your full manuscript online via our online submission service available at www.bentham-mps.org or by FTP submission at www.bentham-ftp.org

For online submission, please provide your complete manuscript in the form of a single zipped folder containing all the material (main text, figures/ illustrations, scanned photographs, tables, chemical structures drawn in ChemDraw) as separate files and a PDF version of the entire manuscript with all the figures/ illustrations / tables / chemical structures etc., embedded in the text exactly in the manner as they should appear in printing. Authors are required to proofread the PDF version of their manuscript before submission. The article will be published exactly as received and the Publishers will not be responsible for any error occurring in the manuscript in this regard.

You may, however, still submit your abstracts and manuscripts through conventional surface mail.

A successful electronic submission of a manuscript will be followed by a system-generated acknowledgement to the principal/corresponding author within 72 hours of the dispatch of the manuscript. Any queries therein should be addressed to mahmood@bentham.org and copied to Jalil@bentham.org

Page Charges:
No page charges will be levied to authors.

Language Editing: Manuscripts submitted containing many English typographical errors will not be published. Authors from non-English language countries are advised to use the services of our professional language editing department prior to submitting their manuscript to the Journal. Please contact Bentham Publishing Services www.benthampublishingservices.com for a language editing quote at e-mail: info@benthampublishingservices.com stating the total number of words of the article to be edited.

Proofs: Authors are sent page proofs. To avoid delays in publication, proofs should be checked immediately for typographical errors and returned within 48 hours. Authors will be charged for excessive changes made at the page proof stage.

Reprints: Each first named author will receive by e-mail a free copy of their article as a PDF file. The PDF file is a watermarked version of the published article which is exclusively for the author's own use and may not be copied or distributed. Reprints may be ordered from the Publisher prior to publication of the article. First named authors may also order a personal print and online subscription of the journal at 50% off the normal subscription rate by contacting the subscription department at e-mail: subscriptions@bentham.org

Bentham Open Access: Accepted articles can be published online for free open access for all to view. Open access publishing provides the maximum dissemination of the article to the largest audience. Authors must pay for this service. All corresponding authors will be asked to indicate whether or not they wish to pay to have their paper made freely available on publication. If authors do not select the Open Access option, then their article will be published with standard subscription-based access at no charge. Open access articles are published under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provide the work is properly cited.

Bentham Science offers authors the choice of open access publication of their articles at a fee of US$ 2,800 per published article which allows indefinite online publication with BOTH Bentham Science, PubMed Central and UK PubMed Central. For more information please contact us at e-mail: openaccess@bentham.org

Reviewing and Promptness of Publication: All papers submitted for publication will be immediately subjected to editorial scrutiny, usually in consultation with members of the Editorial Advisory Board. Every effort will be made to assess the papers quickly. The papers will be typeset and the proofs dispatched to the authors normally within 4 weeks of their acceptance.

Copyright: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism is discovered. By submitting a manuscript the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.

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