Current Signal Transduction Therapy

ISSN: 1574-3624 - Volume 3, 3 Issues, 2008

Instructions for Authors

Online Manuscript Submission: Manuscripts must only be submitted online to the Bentham Science Editorial Office. It is preferable that authors first send an abstract to the editor, prior to submitting the full manuscript. The submitted abstract should outline the intended contents and coverage of the article. Abstracts may be sent either by e-mail to the editorial office at cst@bentham.org or alternatively by the Internet at www.bentham.org/onlAbsSub.htm

A successful electronic submission of a manuscript will be followed by a system-generated acknowledgement to the principal/corresponding author within 72 hours of the dispatch of the manuscript. Any queries therein should be addressed to mahmood@bentham.org and copied to Jalil@bentham.org

After approval of your abstract by the editor, you may submit your full manuscript either by e-mail (file size restricted) or by online submission.

For short review manuscripts, these may be submitted as an e-mail attachment (maximum file size 512 KB) to the editorial office at cst@bentham.org

For online submission of manuscripts, these should be submitted via our online manuscript submission service available at www.bentham-mps.org or by FTP submission at www.bentham-ftp.org

For all online submissions, please provide your complete manuscript in the form of a single zipped folder containing soft copies of all the material (main text in MS word format, figures / illustrations, tables, chemical structures drawn in ChemDraw) as separate files, while a PDF version of the entire manuscript must also be included with all the figures / illustrations / tables / chemical structures etc. embedded in the text exactly in the manner as they should appear in print.

Authors are required to proofread the PDF version of their manuscript before submission. The publisher will not be responsible for any error occurring in the manuscript in this regard.

Conventional Manuscript Submission: Manuscripts may also be submitted by conventional mail to the Co Editors-in-Chief at the following addresses:

Prof. György Kéri
Department of Medicinal Chemistry
Molecular Biology and Pathobiochemistry
Semmelweis University, Budapest
H-1444, Bp. 8. POB 260
1088. Puskin. U. 9.
Budapest, Hungary
Tel: 361- 487-2083
Fax: 361-487-2081
E-mail: Keri@puskin.sote.hu or Keri@vichem.hu

Prof. Axel Ullrich
Department of Molecular Biology
Max Planck Institute
Martinsreed, Germany
Tel: +49-89-8578-2513
Fax: +49-89-857-7866
E-mail: ullrich@biochem.mpg.de

For full-length review articles, the manuscript, written in English, should not exceed 70 pages in length (ca. 30 printed pages) and for mini-reviews a maximum of 40 manuscript pages in length (ca. 15 printed pages). The manuscript should be typed in double spacing throughout on A-4 or American quarto paper. Dot matrix print or any print that is difficult to read is unacceptable. All pages should be numbered. Abbreviations should be defined the first time they are used in the manuscript and a list of abbreviations used should also be provided. Once a manuscript has been accepted pending revisions, please send a computer disk that indicates the program used and this should be written on the label of the disk.

Two copies of the manuscript must accompany the original along with the soft copy of the manuscript on a computer floppy disk(s) in MS Word file format (or created in any other well-known word processing software) should be submitted. To achieve rapid publication, authors are encouraged to e-mail or fax their submissions to the appropriate editorial office (see above) at the same time that they mail the manuscript. For even faster publication, authors are encouraged to submit their entire manuscript via Bentham Science’s online submission service (see above). Authors must provide their full address, telephone and fax numbers with e-mail address with all submissions.

For expedient and speedy reviewing of authors’ manuscripts, authors are strongly advised to include the PDF file of their manuscript on a floppy or zip disk, into the mailing material. At the same time the package is mailed, please also send by e-mail a copy of the PDF file of the manuscript to the editorial office.

Manuscript Organization: The manuscript should be divided as: Title page, abstract and the main text. The text may be subdivided further according to the areas to be discussed. The Acknowledgements (if any) and Reference sections must then follow.

Conflict of Interest: Financial contributions to the work being reported should be clearly acknowledged, as should any potential conflict of interest.

Title Page: The first page should contain the title, the author's full names, institutional affiliations and location, with an asterisk in front of the name of the principal author. The corresponding author should be designated and their full address, business telephone and fax numbers and e-mail address must be stated to receive correspondence and galley proofs.

Abstract: The abstract should not exceed 200 words and should condense the essential features of the review article.

Key Words: Authors must supply up to six key words along with their manuscript.

Text: The main text should begin on a separate page and it may be subdivided into separate sections. The reference numbers should be given in square brackets in the text. Acknowledgements should be kept to a minimum.

Tables:

• Data Tables should be submitted in Microsoft Excel or in Microsoft Word table format.
• Each table should include a title/caption explaining what the table shows. Detailed legends may then follow.
• Tables should be given on separate pages with indications on the left hand margin to the text, as to the appropriate placement of the tables.
• Tables should not contain vertical rules.
• Columns and rows of data should be made visibly distinct by ensuring the borders of each cell display as black lines.
• Tables should be numbered consecutively in order of their citation in the body of the text, with Arabic numerals.
• If a reference is cited in both the table and text, insert a lettered footnote in the table to refer to the numbered reference in the text.
• Tabular data provided as additional files can be submitted as an Excel spreadsheet.

Figures / Illustrations:

All authors must strictly follow the guidelines below for preparing illustrations for publication in Current Signal Transduction Therapy.

Editorial Requirements:

The quality of the illustrations printed in the journal largely depends on the quality of the figures/illustration provided by the author. In preparing artwork or graphics for publication, keep in mind the following points.

• Submit the original artwork or a photographic print of the original for publication.
• Do not submit photocopies. (Hardcopy submission requirement).
• Illustrations should be provided as separate files, not embedded in the text. (Hardcopy submission requirement).
• Remove all color from graphics except for those illustrations (Greyscale), which are intended to be printed in color.
• Good quality of hardcopy originals are a requirement.
• Figures should be referred to as “Fig. (1)”, “Fig. (2)” etc. in the text with figure numbers in bold within round bracket.
• Revised manuscripts should contain a complete set of artwork and photographs.

Technical Details:

• Figures should be provided on high quality, white, smooth opaque paper. (Hardcopy requirement).

Format & Resolution:

• The following file formats can be accepted. (Preference in order of appearance): PDF, TIFF, JPEG, GIF.
• Illustrations must fit a single or double column format on the journal page, according to the following guideline below:

	HEIGHT	WIDTH
SINGLE COLUMN	24 cm (max)	8.5 cm (max)
DOUBLE COLUMN	24 cm (max)	18 cm (max)

• Whenever possible, submit graphics that do not have to be reduced to fit the standard figure size.
• Use the best resolution available (hardcopy submission requirement). For online submission the maximum resolution is 300 dpi.
• Avoid textures and shadings giving a three-dimensional effect to the illustration.
• Symbols and lettering in the illustration should be of similar size.
• Smaller lettering is used.
• Font: Times New Roman or Helvetica is preferable. Font size: 10pt (maximum).
• Line drawings should have clear and sharp lines and should be of uniform density. Moreover, lines should be continuous without any breaks.
• Do not use lines thinner than 1 point.

Color Figures / Illustrations:

• The cost for the first published page of color figures is US$ 730; the second additional page will be for US$ 535, and each subsequent page for US$ 360.
• Color figures should be supplied in CMYK not RGB colors.
• Required resolution for online submission is 300 dpi. In case of hardcopy submission, please use the maximum resolution available. In case the figure(s) are of an inferior quality they will need to be improved either by the author or by the publisher on a charged basis.

Photographs:

Submit high-contrast prints that are of single- or double-column width so that they will not have to be reduced when printed. Negatives are not acceptable. However, in case of hardcopy submission, color illustrations and plates can be published from 35 mm color slides.

Chemical Structures: Chemical structures must be prepared according to the guidelines below.

Structures should be prepared using a suitable drawing program e.g. ChemDraw and provided as separate file, submitted both on disk and in printed formats.

Numbers in bold should identify all chemical structure. If a name is also used to describe the compound, the associated number in bold should be in parenthesis, e.g. “compound (1)”.

Structure Drawing Preferences:

[As according to the ACS style sheet]

Drawing Settings:

Chain angle       120°

Bond spacing    18% of width

Fixed length       14.4 pt (0.500cm, 0.2in)

Bold width          2.0 pt (0.071cm, 0.0278in)

Line width           0.6 pt (0.021cm, 0.0084in)

Margin width       1.6 pt (0.096cm)

Harsh spacing    2.5 pt (0.088cm, 0.0347in)

Text settings:

Font                    Times New Roman / Helvetica

Size                    10pt

Under the Preference Choose:

Units                    points

Tolerances          3 pixels

Under Page Setup Use:

Paper                  US letter

Scale                  100%

References: References: References should be numbered sequentially [in square brackets] in the text and listed in the same order in the reference section.

All references must be complete and accurate. Online citations should include the date of access. Journal titles should conform to the present Index Medicus abbreviations. It is necessary to list all authors if the total number of authors is 6 or less, and for more than 6 authors use 3 authors and then et al. References should be listed in the following Vancouver style:

Typical Paper Reference:

Carter CA, Kane CJ. Therapeutic potential of natural compounds that regulate the activity of protein kinase C. Curr Med Chem. 2004; 11: 2883-902.

Danen EH. Integrins: regulators of tissue function and cancer progression. Curr Pharm Des. 2005; 11: 881-91.

Typical Chapter Reference:

Stevenson WG, Friedman PL. In: Hennekens CH Ed, Clinical trials in cardiovascular disease. Philadelphia, WB Saunders Co. 1999; 217-30.

Page Charges: No page charges will be levied to authors.

Language Editing: Manuscripts submitted containing many English typographical errors will not be published. Authors from non-English language countries are advised to use the services of our professional language editing department prior to submitting their manuscript to the Journal. Please contact Bentham Publishing Services www.benthampublishingservices.com for a language editing quote at e-mail: info@benthampublishingservices.com stating the total number of words of the article to be edited.

Proofs: Authors are sent page proofs. To avoid delays in publication, proofs should be checked immediately for typographical errors and returned within 48 hours. Authors will be charged for excessive changes made at the page proof stage.

Reprints: Each first named author will receive by e-mail a free copy of their article as a PDF file. The PDF file is a watermarked version of the published article which is exclusively for the author's own use and may not be copied or distributed. Reprints may be ordered from the Publisher prior to publication of the article. First named authors may also order a personal print and online subscription of the journal at 50% off the normal subscription rate by contacting the subscription department at e-mail: subscriptions@bentham.org

Bentham Open Access: Accepted articles can be published online for free open access for all to view. Open access publishing provides the maximum dissemination of the article to the largest audience. Authors must pay for this service. All corresponding authors will be asked to indicate whether or not they wish to pay to have their paper made freely available on publication. If authors do not select the Open Access option, then their article will be published with standard subscription-based access at no charge. Open access articles are published under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provide the work is properly cited.

Bentham Science offers authors the choice of open access publication of their articles at a fee of US$ 2,800 per published article which allows indefinite online publication with BOTH Bentham Science and PubMed Central.

Alternatively, authors may choose to publish their article with Bentham Science at a reduced fee for a limited open access period. Bentham Science is the first and only publisher to offer authors the choice at a reduced open access fee to have their article published for a limited open access period. For open access publication for a period of twelve months (limited open access) the per article fee is US$ 1,400 . For more information please contact us at e-mail: openaccess@bentham.org

Reviewing and Promptness of Publication: All papers submitted for publication will be immediately subjected to editorial scrutiny, usually in consultation with members of the Editorial Advisory Board. Every effort will be made to assess the papers quickly. The papers will be typeset and the proofs dispatched to the authors normally within 4 weeks of their acceptance.

Copyright: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism is discovered. By submitting a manuscript the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.