Drug Design Reviews – Online

ISSN: 1567-2697 Volume 2, 2005

Instructions for Authors

Manuscripts must only be submitted online to the Bentham Science’s editorial office via online FTP manuscript submission system available at www.bentham-ftp.org although short manuscripts may also be submitted as an attachment (maximum file size 512 KB) by email ddro@bentham.org to the editorial office.

It is preferable that authors first send an abstract by using the Internet abstract submission facility available at www.bentham.org/abstract or alternatively by e-mail to the editorial office at ddro@bentham.org summarizing the proposed contents of their review article. Once the Editor-in-Chief of the journal has accepted your abstract, you may submit your full manuscript either via our online FTP submission service or by e-mail.

For all online submissions, please provide your complete manuscript in the form of a single zipped folder containing soft copies of all the material (main text in MS word format, figures/ illustrations, scanned photographs, tables, chemical structures drawn in ChemDraw) as separate files, while a PDF version of the entire manuscript MUST also be included with all the figures/ illustrations / tables / chemical structures etc. embedded in the text exactly in the manner as they should appear in print.

Authors are required to proofread the PDF version of their manuscript before submission. The Publishers will not be responsible for any error occurring in the manuscript in this regard.

To facilitate speedy and cost-effective submission of abstracts and manuscripts, an online submission and tracking service via Internet is being offered. Once the Editor-in-Chief of the journal has accepted your abstract, we would prefer that you submit your full manuscript online via our online submission service available at www.bentham-mps.org

Authors must provide their full address, telephone and Fax numbers with E-Mail address with all submissions.

Manuscript Organization: The manuscript should be divided as: Title page, abstract and the main text. The text may be subdivided further according to the areas to be discussed. This should be followed by the Acknowledgement (if any) and Reference sections. The first page should contain the title, the authors’ names (initials and surname only), with an asterisk to mark the name of the principal author.

Conflict of Interest: Financial contributions to the work being reported should be clearly acknowledged, as should any potential conflict of interest.

Abstract: The abstract should not exceed 250 words and it should condense the essential features of the review article, with the focus on the major advances in the field.

Key Words: Authors must supply up to eight key words along with their manuscript.

Text: The main text should begin on a separate page and it may be subdivided into separate sections. For reviews, the article should mention any previous important reviews in the field and contain a comprehensive discussion starting with the general background of the field. It should then go on to discuss the salient features of recent developments. The authors should avoid presenting material that has already been published in a previous review.

Tables:

• Data Tables should be submitted in Microsoft Excel or in Microsoft Word table format.
• Each table should include a title/caption explaining what the table shows. Detailed legends may then follow.
• Tables should be given on separate pages with indications on the left hand margin to the text, as to the appropriate placement of the tables.
• Tables should not contain vertical rules.
• Columns and rows of data should be made visibly distinct by ensuring the borders of each cell display as black lines.
• Tables should be numbered consecutively in order of their citation in the body of the text, with Arabic numerals.
• If a reference is cited in both the table and text, insert a lettered footnote in the table to refer to the numbered reference in the text.
• Tabular data provided as additional files can be submitted as an Excel spreadsheet.

Figures / Illustrations:

All authors must strictly follow the guidelines below for preparing illustrations for publication in Current Neurovascular Research.

Editorial Requirements:

The quality of the illustrations printed in the journal largely depends on the quality of the figures/illustration provided by the author. In preparing artwork or graphics for publication, keep in mind the following points.

• Submit the original artwork or a photographic print of the original for publication.
• Do not submit photocopies. (Hardcopy submission requirement).
• Illustrations should be provided as separate files, not embedded in the text. (Hardcopy submission requirement).
• Remove all color from graphics except for those illustrations (Greyscale), which are intended to be printed in color.
• Good quality of hardcopy originals are a requirement.
• Figures/illustrations cannot be modified or enhanced by the journal production staff.
• Figures should be referred to as “Fig. (1)”, “Fig. (2)” etc. in the text with figure numbers in bold within round bracket.
• Revised manuscripts should contain a complete set of artwork and photographs.

Technical Details:

• Figures should be provided on high quality, white, smooth opaque paper. (Hardcopy requirement).

Format & Resolution:

• The following file formats can be accepted. (Preference in order of appearance): PDF, TIFF, JPEG, GIF.
• Illustrations must fit a single or double column format on the journal page, according to the following guideline below:

	HEIGHT	WIDTH
SINGLE COLUMN	24 cm (max)	8.5 cm (max)
DOUBLE COLUMN	24 cm (max)	18 cm (max)

• Whenever possible, submit graphics that do not have to be reduced to fit the standard figure size.
• Use the best resolution available (hardcopy submission requirement). For online submission the maximum resolution is 300 dpi.
• Avoid textures and shadings giving a three-dimensional effect to the illustration.
• Symbols and lettering in the illustration should be of similar size.
• Smaller lettering is used.
• Font: Times New Roman or Helvetica is preferable. Font size: 10pt (maximum).
• Line drawings should have clear and sharp lines and should be of uniform density. Moreover, lines should be continuous without any breaks.
• Do not use lines thinner than 1 point.

Color Figures / Illustrations:

• One color plate will be published free of charge in eacharticle. The cost for the first additional published page of color figures is US$ 605; the second additional page will be for US$ 440, and each subsequent page for $ 303.
• Color figures should be supplied in CMYK not RGB colors.
• Required resolution for online submission is 300 dpi. In case of hardcopy submission, please use the maximum resolution available.

Chemical Structures: Chemical structures must be prepared according to the guidelines below.

Structures should be prepared using a suitable drawing program e.g. ChemDraw and provided as separate file, submitted both on disk and in printed formats.

Numbers in bold should identify all chemical structure. If a name is also used to describe the compound, the associated number in bold should be in parenthesis, e.g. “compound (1)”.

Structure Drawing Preferences:

[As according to the ACS style sheet]

Drawing Settings:

Chain angle       120°

Bond spacing    18% of width

Fixed length       14.4 pt (0.500cm, 0.2in)

Bold width          2.0 pt (0.071cm, 0.0278in)

Line width           0.6 pt (0.021cm, 0.0084in)

Margin width       1.6 pt (0.096cm)Harsh spacing    2.5 pt (0.088cm, 0.0347in)

Text settings:

Font                    Times New Roman / Helvetica

Size                    10pt

Under the Preference Choose:

Units                    points

Tolerances          3 pixels

Under Page Setup Use:

Paper                  US letter

Scale                  100%

References: For the format of references, see the ACS Style Guide, pp 106-114

Examples:

Journal Reference:

Barton, D.H.R.; Brewster, A.G.; Ley, S.V.; Rosenfield, M.N.J. Chem. Soc. Chem. Commun., 1977, 147, 2356.

Book Reference:

Rahman, A.-U.; Shah, Z. Stereoselective Synthesis in Organic Chemistry, Springer-Verlag: New York, 1993.

Book Chapter Reference:

Wheeler, D.M.S.; Wheeler, M.M. In Studies in Natural Products Chemistry; Atta-ur-Rahman, Ed.; Elsevier Science B.V: Amsterdam, 1994; Vol. 14, pp. 3-46.

Abstracts, unpublished data and personal communications (which can be only included if permission has been obtained) should not be given in the references section but they may be mentioned in the text and details provided as footnotes. All authors of referenced papers must be cited and there must be no use of the short hand version of et al. when citing authors. Abbreviations should be defined the first time that they are used in the manuscript and a list of abbreviations should be provided.

Reviewing and Promptness of Publication: All manuscripts submitted for publication will be immediately subjected to peer-review, usually in consultation with members of the Editorial Advisory Board. All peer-review will be done by the Internet to facilitate rapid review of submitted manuscripts. Authors are encouraged, however, to suggest names of possible referees for their submissions. Every effort will be made to assess manuscripts quickly and the decision conveyed to the authors normally within two weeks of the receipt of the paper. Author’s proofs will be dispatched by E-mail to the authors.

Proofs: Authors are sent page proofs by E-mail as a PDF file. To avoid delays in publication, proofs should be checked immediately for typographical errors and returned within 48 hours. Major changes are not acceptable at the proof stage.

Bentham Open Access: Accepted articles can be published online for free open access for all to view. Open access publishing provides the maximum dissemination of the article to the largest audience. Authors must pay for this service. All corresponding authors will be asked to indicate whether or not they wish to pay to have their paper made freely available on publication. If authors do not select the Open Access option, then their article will be published with standard subscription-based access at no charge. Open access articles are published under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provide the work is properly cited.

Bentham Science offers authors the choice of open access publication of their articles at a fee of US$ 1,500 per published article which allows indefinite online publication with BOTH Bentham Science and PubMed Central. For authors who select this option, Bentham Science will undertake to deposit these articles in PubMed Central and to make these freely available on publication.

Alternatively, authors may choose to publish their article with Bentham Science at a reduced fee for a limited open access period. Bentham Science is the first and only publisher to offer authors the choice at a reduced open access fee to have their article published for a limited open access period. For open access publication for a period of twelve months (limited open access) the per article fee is US$ 750 . For more information please contact us at e-mail: openaccess@bentham.org

Copyright: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism is discovered. By submitting a manuscript the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.

Page Charges: No page charges will be levied to authors.

Online access: The corresponding author will be entitled to free online access to the journal issue in which their article is published. Corresponding authors may also order a personal online subscription of the journal at 50% off the normal subscription rate.